Description：

G-749 is a novel and potent FLT3 inhibitor with IC50 of 0.4 nM, 0.6 nM and 1 nM for FLT3 (WT), FLT3 (D835Y), and Mer, respectively, showing lower potency against other tyrosine kinases.

Chemical Information：

Molecular Weight (MW)		521.41
Formula		C25H25BrN6O2
CAS No.		1457983-28-6
Solubility (25°C) *	DMSO	24 mg/mL warmed (46.02 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.9179 mL	9.5894 mL	19.1788 mL
5 mM	0.3836 mL	1.9179 mL	3.8358 mL
10 mM	0.1918 mL	0.9589 mL	1.9179 mL
50 mM	0.0384 mL	0.1918 mL	0.3836 mL

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