Description：

Fostamatinib (R788), a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 3.

Chemical Information：

Molecular Weight (MW)		580.46
Formula		C23H26FN6O9P
CAS No.		901119-35-5
Solubility (25°C) *	DMSO	116 mg/mL (199.84 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.7228 mL	8.6139 mL	17.2277 mL
5 mM	0.3446 mL	1.7228 mL	3.4455 mL
10 mM	0.1723 mL	0.8614 mL	1.7228 mL
50 mM	0.0345 mL	0.1723 mL	0.3446 mL

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