Description：

EW-7197 is a highly potent, selective, and orally bioavailable TGF-β receptor ALK4/ALK5 inhibitor with IC50 of 13 nM and 11 nM, respectively. Phase 1.

Chemical Information：

Molecular Weight (MW)		399.42
Formula		C22H18FN7
CAS No.		1352608-82-2
Solubility (25°C) *	DMSO	79 mg/mL (197.78 mM)
	Water	Insoluble
	Alcohol	43 mg/mL (107.65 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.5036 mL	12.5182 mL	25.0363 mL
5 mM	0.5007 mL	2.5036 mL	5.0073 mL
10 mM	0.2504 mL	1.2518 mL	2.5036 mL
50 mM	0.0501 mL	0.2504 mL	0.5007 mL

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