Description：

Epacadostat (INCB024360) is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM and displays high selectivity over other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO).

Chemical Information：

Molecular Weight (MW)		438.23
Formula		C11H13BrFN7O4S
CAS No.		1204669-58-8
Solubility (25°C) *	DMSO	87 mg/mL (198.52 mM)
	Water	Insoluble
	Alcohol	53 mg/mL warmed (120.94 mM)

Biological Activity：

Targets IC50

5-HT 13 nM (Ki)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.2819 mL	11.4095 mL	22.8191 mL
5 mM	0.4564 mL	2.2819 mL	4.5638 mL
10 mM	0.2282 mL	1.1410 mL	2.2819 mL
50 mM	0.0456 mL	0.2282 mL	0.4564 mL

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