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ENMD-2076 L-(+)-Tartaric acid

ENMD-2076 L-(+)-Tartaric acid

Catalog Number: CC2174 Rank: comment rank 5

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Description:

ENMD-2076 L-(+)-Tartaric acid is the tartaric acid of ENMD-2076, selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.86 nM, 25-fold more selective for Aurora A than Aurora B and less potent to VEGFR2/KDR and VEGFR3, FGFR1 and FGFR2 and PDGFRα. Phase 2.

Chemical Information:

Molecular Weight (MW) 525.56
Formula

 

C25H31N7O6

 

CAS No. 1291074-87-7
Solubility (25°C) * DMSO 100 mg/mL warmed(190.27 mM)
Water Insoluble
Alcohol Insoluble


Biological Activity:

Targets
IC50
β-lactamase
33 mM (Kd)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.9027 mL 9.5137 mL 19.0273 mL
5 mM 0.3805 mL 1.9027 mL 3.8055 mL
10 mM 0.1903 mL 0.9514 mL 1.9027 mL
50 mM 0.0381 mL 0.1903 mL 0.3805 mL


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