Description：

ENMD-2076 has selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.86 nM, 25-fold selective for Aurora A than over Aurora B and less potent to VEGFR2/KDR and VEGFR3, FGFR1 and FGFR2 and PDGFRα. Phase 2.

Chemical Information：

Molecular Weight (MW)		375.47
Formula		C21H25N7
CAS No.		934353-76-1
Solubility (25°C) *	DMSO	105 mg/mL (279.64 mM)
	Water	1 mg/mL (2.66 mM)
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.6633 mL	13.3166 mL	26.6333 mL
5 mM	0.5327 mL	2.6633 mL	5.3267 mL
10 mM	0.2663 mL	1.3317 mL	2.6633 mL
50 mM	0.0533 mL	0.2663 mL	0.5327 mL

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