Description：

Dibenzazepine (YO-01027) is a dipeptidic γ-secretase inhibitor with IC50 of 2.6 nM and 2.9 nM in cell-free assays for APPL and Notch cleavage, respectively.

Chemical Information：

Molecular Weight (MW)		463.48
Formula		C26H23F2N3O3
CAS No.		209984-56-5
Solubility (25°C) *	DMSO	92 mg/mL (198.49 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1576 mL	10.7880 mL	21.5759 mL
5 mM	0.4315 mL	2.1576 mL	4.3152 mL
10 mM	0.2158 mL	1.0788 mL	2.1576 mL
50 mM	0.0432 mL	0.2158 mL	0.4315 mL

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