Description：

Decitabine is a DNA methyltransferase inhibitor, incorporating into DNA and resulting in hypomethylation of DNA and intra-S-phase arrest of DNA replication. It is used to treat myelodysplastic syndrome (MDS).

Chemical Information：

Molecular Weight (MW)		228.21
Formula		C8H12N4O4
CAS No.		2353-33-5
Solubility (25°C) *	DMSO	45 mg/mL (197.18 mM)
	Water	10 mg/mL (43.81 mM)
	Alcohol	Insoluble

Biological Activity：

Targets IC50

p53

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	4.3819 mL	21.9096 mL	43.8193 mL
5 mM	0.8764 mL	4.3819 mL	8.7639 mL
10 mM	0.4382 mL	2.1910 mL	4.3819 mL
50 mM	0.0876 mL	0.4382 mL	0.8764 mL

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