Description：

DAPT (GSI-IX) is a novel γ-secretase inhibitor, which inhibits Aβ production with IC50 of 20 nM in HEK 293 cells.

Chemical Information：

Molecular Weight (MW)		432.46
Formula		C23H26F2N2O4
CAS No.		208255-80-5
Solubility (25°C) *	DMSO	86 mg/mL (198.86 mM)
	Water	Insoluble
	Alcohol	50 mg/mL (115.61 mM)

Biological Activity：

Targets IC50

IκBα 10 μM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.3124 mL	11.5618 mL	23.1235 mL
5 mM	0.4625 mL	2.3124 mL	4.6247 mL
10 mM	0.2312 mL	1.1562 mL	2.3124 mL
50 mM	0.0462 mL	0.2312 mL	0.4625 mL

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