Description：

Daphnetin, a natural coumarin derivative, is a protein kinase inhibitor, inhibits EGFR, PKA and PKC with IC50 of 7.67 μM, 9.33 μM and 25.01 μM, respectively, also known to exhibit anti-inflammatory and anti-oxidant activities.

Chemical Information：

Molecular Weight (MW)		178.14
Formula		C9H6O4
CAS No.		486-35-1
Solubility (25°C) *	DMSO	35 mg/mL (196.47 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

LPA3 LPA1 0.93 μM (Ki) [1 0.34 μM (Ki)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	5.6136 mL	28.0678 mL	56.1356 mL
5 mM	1.1227 mL	5.6136 mL	11.2271 mL
10 mM	0.5614 mL	2.8068 mL	5.6136 mL
50 mM	0.1123 mL	0.5614 mL	1.1227 mL

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