Description：

7,8-Dihydroxyflavone acts as a potent and selective small-molecule agonist of the TrkB receptor (Kd ≈ 320 nM), the main signaling receptor of brain-derived neurotrophic factor (BDNF).

Chemical Information：

Molecular Weight (MW)		254.24
Formula		C15H10O4
CAS No.		38183-03-8
Solubility (25°C) *	DMSO	50 mg/mL (196.66 mM)
	Water	Insoluble
	Alcohol	1 mg/mL (3.93 mM)

Biological Activity：

Targets IC50

PPARδ PPARγ PPARα 1.8 μM 1 nM 0.85 μM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.9333 mL	19.6665 mL	39.3329 mL
5 mM	0.7867 mL	3.9333 mL	7.8666 mL
10 mM	0.3933 mL	1.9666 mL	3.9333 mL
50 mM	0.0787 mL	0.3933 mL	0.7867 mL

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