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CX-6258 HCl

CX-6258 HCl

Catalog Number: CC7197 Rank: comment rank 5

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Description:

CX-6258 HCl is a potent, orally efficacious pan-Pim kinase inhibitor with IC50 of 5 nM, 25 nM and 16 nM for Pim1, Pim2, and Pim3, respectively.

Chemical Information:

Molecular Weight (MW) 498.40
Formula

 

C26H24ClN3O3.HCl

 

CAS No. 1353859-00-3
Solubility (25°C) * DMSO 57 mg/mL warmed (114.36 mM)
Water 89 mg/mL warmed (178.57 mM)
Alcohol 1 mg/mL warmed (2.0 mM)


Biological Activity:

Targets
IC50
mTOR
2-10 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.0064 mL 10.0321 mL 20.0642 mL
5 mM 0.4013 mL 2.0064 mL 4.0128 mL
10 mM 0.2006 mL 1.0032 mL 2.0064 mL
50 mM 0.0401 mL 0.2006 mL 0.4013 mL


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