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Curcumin

Curcumin

Catalog Number: CC2004 Rank: comment rank 5

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Description:

Curcumin is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). It is an inhibitor of p300 histone acetylatransferase(IC50~25 μM) and Histone deacetylase; activates Nrf2 pathway and supresses the activation of transcription factor NF-κB.

Chemical Information:

Molecular Weight (MW) 368.38
Formula

 

C21H20O6

 

CAS No. 458-37-7
Solubility (25°C) * DMSO 73 mg/mL (198.16 mM)
Water Insoluble
Alcohol Insoluble


Biological Activity:

Targets
IC50
GSK-3β
60 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.7146 mL 13.5729 mL 27.1459 mL
5 mM 0.5429 mL 2.7146 mL 5.4292 mL
10 mM 0.2715 mL 1.3573 mL 2.7146 mL
50 mM 0.0543 mL 0.2715 mL 0.5429 mL


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