Description：

CP-724714 is a potent, selective inhibitor of HER2/ErbB2 with IC50 of 10 nM, >640-fold selectivity against EGFR, InsR, IRG-1R, PDGFR, VEGFR2, Abl, Src, c-Met etc in cell-free assays. Phase 2.

Chemical Information：

Molecular Weight (MW)		469.53
Formula		C27H27N5O3
CAS No.		537705-08-1
Solubility (25°C) *	DMSO	94 mg/mL (200.2 mM)
	Water	Insoluble
	Alcohol	94 mg/mL (200.2 mM)

Biological Activity：

Targets IC50

NAMPT 0.09 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1298 mL	10.6489 mL	21.2979 mL
5 mM	0.4260 mL	2.1298 mL	4.2596 mL
10 mM	0.2130 mL	1.0649 mL	2.1298 mL
50 mM	0.0426 mL	0.2130 mL	0.4260 mL

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