Description：

Clofazimine is a rhimophenazine dye, originally developed for the treatment of tuberculosis, it has both antimicrobial and antiinflammatory activity, postulated mechanisms of action include intercalation of clofazimine with bacterial DNA and increasing levels of cellular phospholipase A2.

Chemical Information：

Molecular Weight (MW)		473.4
Formula		C27H22Cl2N4
CAS No.		2030-63-9
Solubility (25°C) *	DMSO	5 mg/mL (10.56 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

ATM DNA-PK PI3K MLCK ATR 150 nM 16 nM 3 nM 170 nM 1.8 μM [12]

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1124 mL	10.5619 mL	21.1238 mL
5 mM	0.4225 mL	2.1124 mL	4.2248 mL
10 mM	0.2112 mL	1.0562 mL	2.1124 mL
50 mM	0.0422 mL	0.2112 mL	0.4225 mL

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