Description：

Clinofibrate inhibits hydroxymethylglutaryl coenzyme A reductase (HMGCR) with IC50 of 0.47 mM, is a lipid-lowering agent used for controlling high cholesterol and triacylglyceride levels in the blood.

Chemical Information：

Molecular Weight (MW)		468.58
Formula		C28H36O6
CAS No.		30299-08-2
Solubility (25°C) *	DMSO	94 mg/mL (200.6 mM)
	Water	Insoluble
	Alcohol	94 mg/mL (200.6 mM)

Biological Activity：

Targets IC50

p35/CDK5 cyclin D1/CDK4 cyclin H/CDK7 cyclin A/CDK2 cyclin E/CDK2 0.265 μM 0.160 μM 0.150 μM 45 nM 0.363 μM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1341 mL	10.6705 mL	21.3411 mL
5 mM	0.4268 mL	2.1341 mL	4.2682 mL
10 mM	0.2134 mL	1.0671 mL	2.1341 mL
50 mM	0.0427 mL	0.2134 mL	0.4268 mL

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