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ADX-47273

ADX-47273

Catalog Number: CC2846 Rank: comment rank 5

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$ 147.00
$ 259.00
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Description:

ADX47273 is a potent and specific mGlu5 positive allosteric modulator(PAM) with EC50 of 0.17 μM, showing no activity at other mGlu subtypes.

Chemical Information:

Molecular Weight (MW) 369.36
Formula

 

C20H17F2N3O2

 

CAS No. 851881-60-2
Solubility (25°C) * DMSO 74 mg/mL (200.34 mM)
Water Insoluble
Alcohol 30 mg/mL (81.22 mM)


Biological Activity:

Targets
IC50
p38α p38β
50 nM 100 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.7074 mL 13.5369 mL 27.0739 mL
5 mM 0.5415 mL 2.7074 mL 5.4148 mL
10 mM 0.2707 mL 1.3537 mL 2.7074 mL
50 mM 0.0541 mL 0.2707 mL 0.5415 mL


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