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Ciclopirox ethanolamine

Ciclopirox ethanolamine

Catalog Number: CC3175 Rank: comment rank 5

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Description:

Ciclopirox ethanolamine (Ciclopirox olamine, HOE 296) is a broad-spectrum antifungal agent working as an iron chelator.

Chemical Information:

Molecular Weight (MW) 268.35
Formula

 

C12H17NO2.C2H7NO

 

CAS No. 41621-49-2
Solubility (25°C) * DMSO 6 mg/mL (22.35 mM)
Water Insoluble
Alcohol 30 mg/mL (111.79 mM)


Biological Activity:

Targets
IC50
PI3Kγ PI3Kδ PI3Kα mTOR PI3Kβ
14 nM 7 nM 5 nM 17 nM (Ki) 27 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 3.7265 mL 18.6324 mL 37.2648 mL
5 mM 0.7453 mL 3.7265 mL 7.4530 mL
10 mM 0.3726 mL 1.8632 mL 3.7265 mL
50 mM 0.0745 mL 0.3726 mL 0.7453 mL


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