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CHIR-99021 (CT99021) HCl

CHIR-99021 (CT99021) HCl

Catalog Number: CC3080 Rank: comment rank 5

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$ 118.00
$ 399.00
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Description:

CHIR-99021 HCl (CT99021) is hydrochloride of CHIR-99021, which is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM; CHIR-99021 shows greater than 500-fold selectivity for GSK-3 versus its closest homologs Cdc2 and ERK2.

Chemical Information:

Molecular Weight (MW) 501.8
Formula

 

C22H18Cl2N8.HCl

 

CAS No. 1797989-42-4
Solubility (25°C) * DMSO 93 mg/mL (185.33 mM)
Water Insoluble
Alcohol 2 mg/mL (3.98 mM)


Biological Activity:

Targets
IC50
5-HT
0.95 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.9928 mL 9.9641 mL 19.9283 mL
5 mM 0.3986 mL 1.9928 mL 3.9857 mL
10 mM 0.1993 mL 0.9964 mL 1.9928 mL
50 mM 0.0399 mL 0.1993 mL 0.3986 mL


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