Description：

Brigatinib (AP26113) is a potent and selective ALK (IC50, 0.6 nM) and ROS1 (IC50, 0.9 nM) inhibitor. It also inhibits ROS1, FLT3, and mutant variants of FLT3 (D835Y) and EGFR with lower potentcy.

Chemical Information：

Molecular Weight (MW)		584.09
Formula		C29H39ClN7O2P
CAS No.		1197953-54-0
Solubility (25°C) *	DMSO	1 mg/mL warmed (1.71 mM)
	Water	Insoluble
	Alcohol	43 mg/mL warmed (73.61 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.7121 mL	8.5603 mL	17.1206 mL
5 mM	0.3424 mL	1.7121 mL	3.4241 mL
10 mM	0.1712 mL	0.8560 mL	1.7121 mL
50 mM	0.0342 mL	0.1712 mL	0.3424 mL

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