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Brefeldin A

Brefeldin A

Catalog Number: CC7202 Rank: comment rank 5

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Description:

Brefeldin A is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells, induces cancer cell differentiation and apoptosis.

Chemical Information:

Molecular Weight (MW) 280.36
Formula

 

C16H24O4

 

CAS No. 20350-15-6
Solubility (25°C) * DMSO 4 mg/mL (14.26 mM)
Water Insoluble
Alcohol Insoluble


Biological Activity:

Targets
IC50
p110β p110δ p110α p110γ
166 nM 116 nM 52-99 nM 262 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 3.5668 mL 17.8342 mL 35.6684 mL
5 mM 0.7134 mL 3.5668 mL 7.1337 mL
10 mM 0.3567 mL 1.7834 mL 3.5668 mL
50 mM 0.0713 mL 0.3567 mL 0.7134 mL


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