Description：

BMY 7378 is a multi-targeted inhibitor of α2C-adrenoceptor and α1D-adrenoceptor with pK_i of 6.54 and 8.2, respectively, and acts as a mixed agonist and antagonist for 5-HT1A receptor with pK_i of 8.3.

Chemical Information：

Molecular Weight (MW)		458.42
Formula		C22H31N3O3.2HCl
CAS No.		21102-95-4
Solubility (25°C) *	DMSO	92 mg/mL (200.68 mM)
	Water	92 mg/mL (200.68 mM)
	Alcohol	20 mg/mL (43.62 mM)

Biological Activity：

Targets IC50

Caspase-1 0.8 nM (Ki)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1814 mL	10.9070 mL	21.8141 mL
5 mM	0.4363 mL	2.1814 mL	4.3628 mL
10 mM	0.2181 mL	1.0907 mL	2.1814 mL
50 mM	0.0436 mL	0.2181 mL	0.4363 mL

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