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Biochanin A

Biochanin A

Catalog Number: CC2533 Rank: comment rank 5

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Description:

Biochanin A, an O-methylated isoflavone from Trifolium pratense, inhibits protein tyrosine kinase (PTK) of epidermal growth factor receptor with IC50 values of 91.5 μM.

Chemical Information:

Molecular Weight (MW) 284.26
Formula

 

C16H12O5

 

CAS No. 491-80-5
Solubility (25°C) * DMSO 57 mg/mL (200.52 mM)
Water Insoluble
Alcohol 9 mg/mL (31.66 mM)


Biological Activity:

Targets
IC50
JAK2V617F JAK2 JAK2
0.245 nM (Ki) [ 3 nM 0.288 nM (Ki)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 3.5179 mL 17.5895 mL 35.1791 mL
5 mM 0.7036 mL 3.5179 mL 7.0358 mL
10 mM 0.3518 mL 1.7590 mL 3.5179 mL
50 mM 0.0704 mL 0.3518 mL 0.7036 mL


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