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BIBR 1532

BIBR 1532

Catalog Number: CC1342 Rank: comment rank 5

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$ 329.00
$ 77.00
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Description:

BIBR 1532 is a potent, selective, non-competitive telomerase inhibitor with IC50 of 100 nM in a cell-free assay. No inhibition of DNA and RNA polymerases, including HIV reverse transcriptase were observed at concentrations vastly exceeding the IC50 for telomerase.

Chemical Information:

Molecular Weight (MW) 331.36
Formula

 

C21H17NO3

 

CAS No. 321674-73-1
Solubility (25°C) * DMSO 66 mg/mL (199.17 mM)
Water Insoluble
Alcohol 3 mg/mL (9.05 mM)


Biological Activity:

Targets
IC50
GK
42 nM (EC50) [1


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 3.0179 mL 15.0893 mL 30.1787 mL
5 mM 0.6036 mL 3.0179 mL 6.0357 mL
10 mM 0.3018 mL 1.5089 mL 3.0179 mL
50 mM 0.0604 mL 0.3018 mL 0.6036 mL


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