Description：

BI-D1870 is an ATP-competitive inhibitor of S6 ribosome for RSK1/2/3/4 with IC50 of 31 nM/24 nM/18 nM/15 nM in cell-free assays, respectively; 10- to 100-fold selectivity for RSK than MST2, GSK-3β, MARK3, CK1 and Aurora B.

Chemical Information：

Molecular Weight (MW)		391.42
Formula		C19H23F2N5O2
CAS No.		501437-28-1
Solubility (25°C) *	DMSO	78 mg/mL (199.27 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

Smo (human) Smo (mouse) 2.5 nM 1.3 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.5548 mL	12.7740 mL	25.5480 mL
5 mM	0.5110 mL	2.5548 mL	5.1096 mL
10 mM	0.2555 mL	1.2774 mL	2.5548 mL
50 mM	0.0511 mL	0.2555 mL	0.5110 mL

Bought notes(bought amounts latest0)

No one bought this product

Total 0 records, divided into1 pages. First Prev Next Last