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Ac-DEVD-CHO

Ac-DEVD-CHO

Catalog Number: CC8057 Rank: comment rank 5

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Description:

Ac-DEVD-CHO is a potent aldehyde inhibitor of Group II caspases with Ki values of 0.2 nM and 0.3 nM for for caspase-3 and caspase-7, respectively. Weak inhibition for caspase-2.

Chemical Information:

Molecular Weight (MW) 502.47
Formula

 

C20H30N4O11

 

CAS No. 169332-60-9
Solubility (25°C) * DMSO
Water 100 mg/mL (199.01 mM)
Alcohol


Biological Activity:

Targets
IC50
p110α mTOR p110δ p110γ DNA-PK p110β
2 nM 30 nM 3 nM 15 nM 23 nM 3 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.9902 mL 9.9508 mL 19.9017 mL
5 mM 0.3980 mL 1.9902 mL 3.9803 mL
10 mM 0.1990 mL 0.9951 mL 1.9902 mL
50 mM 0.0398 mL 0.1990 mL 0.3980 mL


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