Description：

Y-27632 2HCl is a selective ROCK1 (p160ROCK) inhibitor with K_i of 140 nM in a cell-free assay, exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, MLCK and PAK.

Chemical Information：

Molecular Weight (MW)		320.26
Formula		C14H21N3O.2HCl
CAS No.		129830-38-2
Solubility (25°C) *	DMSO	64 mg/mL warmed (199.83 mM)
	Water	14 mg/mL (43.71 mM)
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.1225 mL	15.6123 mL	31.2246 mL
5 mM	0.6245 mL	3.1225 mL	6.2449 mL
10 mM	0.3122 mL	1.5612 mL	3.1225 mL
50 mM	0.0624 mL	0.3122 mL	0.6245 mL

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