Description：

XAV-939 selectively inhibits Wnt/β-catenin-mediated transcription through tankyrase1/2 inhibition with IC50 of 11 nM/4 nM in cell-free assays, regulates axin levels and does not affect CRE, NF-κB or TGF-β.

Chemical Information：

Molecular Weight (MW)		312.31
Formula		C14H11F3N2OS
CAS No.		284028-89-3
Solubility (25°C) *	DMSO	12 mg/mL (38.42 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.2019 mL	16.0097 mL	32.0195 mL
5 mM	0.6404 mL	3.2019 mL	6.4039 mL
10 mM	0.3202 mL	1.6010 mL	3.2019 mL
50 mM	0.0640 mL	0.3202 mL	0.6404 mL

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