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Venetoclax (ABT-199, GDC-0199)

Venetoclax (ABT-199, GDC-0199)

Catalog Number: CC8204 Rank: comment rank 5

Size Price Qty
$ 189.00
$ 679.00
Total:
    
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Description:

Venetoclax (ABT-199, GDC-0199) is a Bcl-2-selective inhibitor with Ki of <0.01 nM in cell-free assays, >4800-fold more selective versus Bcl-xL and Bcl-w, and no activity to Mcl-1. Phase 3.

Chemical Information:

Molecular Weight (MW) 868.44
Formula

 

C45H50ClN7O7S

 

CAS No. 1257044-40-8
Solubility (25°C) * DMSO 100 mg/mL warmed (115.14 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.1515 mL 5.7575 mL 11.5149 mL
5 mM 0.2303 mL 1.1515 mL 2.3030 mL
10 mM 0.1151 mL 0.5757 mL 1.1515 mL
50 mM 0.0230 mL 0.1151 mL 0.2303 mL


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