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Vatalanib (PTK787) 2HCl

Vatalanib (PTK787) 2HCl

Catalog Number: CC1257 Rank: comment rank 5

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Description:

Vatalanib (PTK787) 2HCl is an inhibitor of VEGFR2/KDR with IC50 of 37 nM in a cell-free assay, less potent against VEGFR1/Flt-1, 18-fold against VEGFR3/Flt-4. Phase 3.

Chemical Information:

Molecular Weight (MW) 419.73
Formula

 

C20H15ClN4.2HCl

 

CAS No. 212141-51-0
Solubility (25°C) * DMSO 85 mg/mL (202.51 mM)
Water 10 mg/mL (23.82 mM)
Alcohol 6 mg/mL (14.29 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.3825 mL 11.9124 mL 23.8248 mL
5 mM 0.4765 mL 2.3825 mL 4.7650 mL
10 mM 0.2382 mL 1.1912 mL 2.3825 mL
50 mM 0.0476 mL 0.2382 mL 0.4765 mL


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