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UNC2025

UNC2025

Catalog Number: CC7732 Rank: comment rank 5

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$ 102.00
$ 312.00
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Description:

UNC2025 is a potent and orally bioavailable dual MER/FLT3 inhibitor with IC50 of 0.74 nM and 0.8 nM, respectively, about 20-fold selectivity over Axl and Tyro3.

Chemical Information:

Molecular Weight (MW) 513.12
Formula

 

C28H41ClN6O

 

CAS No. 1429881-91-3(free base)
Solubility (25°C) * DMSO 25 mg/mL warmed (48.72 mM)
Water 100 mg/mL (194.88 mM)
Alcohol 8 mg/mL warmed (15.59 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.9489 mL 9.7443 mL 19.4886 mL
5 mM 0.3898 mL 1.9489 mL 3.8977 mL
10 mM 0.1949 mL 0.9744 mL 1.9489 mL
50 mM 0.0390 mL 0.1949 mL 0.3898 mL


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