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U0126-EtOH

U0126-EtOH

Catalog Number: CC1258 Rank: comment rank 5

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Description:

U0126-EtOH is a highly selective inhibitor of MEK1/2 with IC50 of 0.07 μM/0.06 μM in cell-free assays, 100-fold higher affinity for ΔN3-S218E/S222D MEK than PD98059.

Chemical Information:

Molecular Weight (MW) 426.56
Formula

 

C18H16N6S2.C2H6O

 

CAS No. 1173097-76-1
Solubility (25°C) * DMSO 85 mg/mL warmed (199.26 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.3443 mL 11.7217 mL 23.4434 mL
5 mM 0.4689 mL 2.3443 mL 4.6887 mL
10 mM 0.2344 mL 1.1722 mL 2.3443 mL
50 mM 0.0469 mL 0.2344 mL 0.4689 mL


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