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TPCA-1

TPCA-1

Catalog Number: CC2980 Rank: comment rank 5

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Description:

TPCA-1 is an inhibitor of IKK-2 with IC50 of 17.9 nM in a cell-free assay, inhibits NF-κB pathway, exhibits 22-fold selectivity over IKK-1.

Chemical Information:

Molecular Weight (MW) 279.29
Formula

 

C12H10FN3O2

 

CAS No. 507475-17-4
Solubility (25°C) * DMSO 56 mg/mL (200.5 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 3.5805 mL 17.9025 mL 35.8051 mL
5 mM 0.7161 mL 3.5805 mL 7.1610 mL
10 mM 0.3581 mL 1.7903 mL 3.5805 mL
50 mM 0.0716 mL 0.3581 mL 0.7161 mL


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