Description：

Tivantinib (ARQ 197) is the first non-ATP-competitive c-Met inhibitor with K_i of 0.355 μM in a cell-free assay, little activity to Ron, and no inhibition to EGFR, InsR, PDGFRα or FGFR1/4. Phase 3.

Chemical Information：

Molecular Weight (MW)		369.42
Formula		C23H19N3O2
CAS No.		905854-02-6
Solubility (25°C) *	DMSO	73 mg/mL (197.6 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.7069 mL	13.5347 mL	27.0695 mL
5 mM	0.5414 mL	2.7069 mL	5.4139 mL
10 mM	0.2707 mL	1.3535 mL	2.7069 mL
50 mM	0.0541 mL	0.2707 mL	0.5414 mL

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