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THZ1 2HCl

THZ1 2HCl

Catalog Number: CC7705 Rank: comment rank 5

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Description:

THZ1 is a covalent CDK7 inhibitor which has the unprecedented ability to target a remote cysteine residue located outside of the canonical kinase domain, providing an unanticipated means of achieving selectivity for CDK7.

Chemical Information:

Molecular Weight (MW) 638.97
Formula

 

C31H30Cl3N7O2

 

CAS No. 1604810-83-4(free base)
Solubility (25°C) * DMSO 100 mg/mL (156.5 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.5650 mL 7.8251 mL 15.6502 mL
5 mM 0.3130 mL 1.5650 mL 3.1300 mL
10 mM 0.1565 mL 0.7825 mL 1.5650 mL
50 mM 0.0313 mL 0.1565 mL 0.3130 mL


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