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Thalidomide

Thalidomide

Catalog Number: CC1349 Rank: comment rank 5

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Description:

Thalidomide was introduced as a sedative drug, immunomodulatory agent and also is investigated for treating symptoms of many cancers. Thalidomide inhibits an E3 ubiquitin ligase, which is a CRBN-DDB1-Cul4A complex.

Chemical Information:

Molecular Weight (MW) 258.23
Formula

 

C13H10N2O4

 

CAS No. 50-35-1
Solubility (25°C) * DMSO 51 mg/mL (197.49 mM)
Water Insoluble
Alcohol 2 mg/mL (7.74 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 3.8725 mL 19.3626 mL 38.7252 mL
5 mM 0.7745 mL 3.8725 mL 7.7450 mL
10 mM 0.3873 mL 1.9363 mL 3.8725 mL
50 mM 0.0775 mL 0.3873 mL 0.7745 mL


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