Description：

TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM, less potent to Flt3 and RET with IC50 of 25 nM and 17 nM in cell-free assays, ~30-fold selective for JAK2 than JAK3, sensitive to JAK2V617F and MPLW515L/K mutations.

Chemical Information：

Molecular Weight (MW)		509.67
Formula		C26H35N7O2S
CAS No.		936091-14-4
Solubility (25°C) *	DMSO	102 mg/mL (200.12 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.9621 mL	9.8103 mL	19.6205 mL
5 mM	0.3924 mL	1.9621 mL	3.9241 mL
10 mM	0.1962 mL	0.9810 mL	1.9621 mL
50 mM	0.0392 mL	0.1962 mL	0.3924 mL

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