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AZD3514

AZD3514

Catalog Number: CC7196 Rank: comment rank 5

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$ 329.00
$ 539.00
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Description:

AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression.Phase 1.

Chemical Information:

Molecular Weight (MW) 519.56
Formula

 

C25H32F3N7O2

 

CAS No. 1240299-33-5
Solubility (25°C) * DMSO 100 mg/mL (192.47 mM)
Water Insoluble
Alcohol 100 mg/mL (192.47 mM)


Biological Activity:

Targets
IC50
PI3Kα PI3Kβ PI3Kγ PI3Kδ PI4KIIIβ
39 nM 0.59 μM 16 nM 0.12 μM 19 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.9247 mL 9.6235 mL 19.2471 mL
5 mM 0.3849 mL 1.9247 mL 3.8494 mL
10 mM 0.1925 mL 0.9624 mL 1.9247 mL
50 mM 0.0385 mL 0.1925 mL 0.3849 mL


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