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TAK-733

TAK-733

Catalog Number: CC2773 Rank: comment rank 5

Size Price Qty
$ 118.00
$ 224.00
$ 679.00
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Description:

TAK-733 is a potent and selective MEK allosteric site inhibitor for MEK1 with IC50 of 3.2 nM, inactive to Abl1, AKT3, c-RAF, CamK1, CDK2, c-Met, etc. Phase 1.

Chemical Information:

Molecular Weight (MW) 504.23
Formula

 

C17H15F2IN4O4

 

CAS No. 1035555-63-5
Solubility (25°C) * DMSO 101 mg/mL (200.3 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.9832 mL 9.9161 mL 19.8322 mL
5 mM 0.3966 mL 1.9832 mL 3.9664 mL
10 mM 0.1983 mL 0.9916 mL 1.9832 mL
50 mM 0.0397 mL 0.1983 mL 0.3966 mL


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