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TAK-715

TAK-715

Catalog Number: CC3084 Rank: comment rank 5

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$ 102.00
$ 329.00
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Description:

TAK-715 is a p38 MAPK inhibitor for p38α with IC50 of 7.1 nM, 28-fold more selective for p38α over p38β, no inhibition to p38γ/δ, JNK1, ERK1, IKKβ, MEKK1 or TAK1. Phase 2.

Chemical Information:

Molecular Weight (MW) 399.51
Formula

 

C24H21N3OS

 

CAS No. 303162-79-0
Solubility (25°C) * DMSO 80 mg/mL (200.24 mM)
Water Insoluble
Alcohol 16 mg/mL (40.04 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.5031 mL 12.5153 mL 25.0307 mL
5 mM 0.5006 mL 2.5031 mL 5.0061 mL
10 mM 0.2503 mL 1.2515 mL 2.5031 mL
50 mM 0.0501 mL 0.2503 mL 0.5006 mL


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