Description：

TAK-659 is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most other kinases, but potent toward both SYK and FLT3.

Chemical Information：

Molecular Weight (MW)		380.85
Formula		C17H21FN6 .HCl
CAS No.		1952251-28-3
Solubility (25°C) *	DMSO	Insoluble
	Water	4 mg/mL warmed (10.5 mM)
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.6257 mL	13.1285 mL	26.2571 mL
5 mM	0.5251 mL	2.6257 mL	5.2514 mL
10 mM	0.2626 mL	1.3129 mL	2.6257 mL
50 mM	0.0525 mL	0.2626 mL	0.5251 mL

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