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SNS-314 Mesylate

SNS-314 Mesylate

Catalog Number: CC1310 Rank: comment rank 5

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Description:

SNS-314 Mesylate is a potent and selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 9 nM, 31 nM, and 3 nM, respectively. It is less potent to Trk A/B, Flt4, Fms, Axl, c-Raf and DDR2. Phase 1.

Chemical Information:

Molecular Weight (MW) 527.04
Formula

 

C18H15ClN6OS2.CH4O3S

 

CAS No. 1146618-41-8
Solubility (25°C) * DMSO 105 mg/mL (199.22 mM)
Water 6 mg/mL (11.38 mM)
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.8974 mL 9.4869 mL 18.9739 mL
5 mM 0.3795 mL 1.8974 mL 3.7948 mL
10 mM 0.1897 mL 0.9487 mL 1.8974 mL
50 mM 0.0379 mL 0.1897 mL 0.3795 mL


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