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SN-38

SN-38

Catalog Number: CC5064 Rank: comment rank 5

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Description:

SN-38 is an active metabolite of CPT-11, inhibits DNA topoisomerase I, DNA synthesis and causes frequent DNA single-strand breaks.

Chemical Information:

Molecular Weight (MW) 392.4
Formula

 

C22H20N2O5

 

CAS No. 86639-52-3
Solubility (25°C) * DMSO 21 mg/mL (53.51 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.5484 mL 12.7421 mL 25.4842 mL
5 mM 0.5097 mL 2.5484 mL 5.0968 mL
10 mM 0.2548 mL 1.2742 mL 2.5484 mL
50 mM 0.0510 mL 0.2548 mL 0.5097 mL


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