Description：

SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/ 0.22 μM, no activity towards Erk1, MKK3, MKK4, c-JUN, PKC, PKA, or CamKII;capable of transport through the blood-brain barrier.

Chemical Information：

Molecular Weight (MW)		335.35
Formula		C16H12F3N3S
CAS No.		305350-87-2
Solubility (25°C) *	DMSO	67 mg/mL (199.79 mM)
	Water	Insoluble
	Alcohol	7 mg/mL (20.87 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.9820 mL	14.9098 mL	29.8196 mL
5 mM	0.5964 mL	2.9820 mL	5.9639 mL
10 mM	0.2982 mL	1.4910 mL	2.9820 mL
50 mM	0.0596 mL	0.2982 mL	0.5964 mL

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