Description：

Silmitasertib (CX-4945) is a potent and selective inhibitor of CK2 (casein kinase 2) with IC50 of 1 nM in a cell-free assay, less potent to Flt3, Pim1 and CDK1 (inactive in cell-based assay). Phase 1/2.

Chemical Information：

Molecular Weight (MW)		349.77
Formula		C19H12ClN3O2
CAS No.		1009820-21-6
Solubility (25°C) *	DMSO	16 mg/mL (45.74 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.8590 mL	14.2951 mL	28.5902 mL
5 mM	0.5718 mL	2.8590 mL	5.7180 mL
10 mM	0.2859 mL	1.4295 mL	2.8590 mL
50 mM	0.0572 mL	0.2859 mL	0.5718 mL

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