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Description:
AZ191 is a potent and selective DYRK1B inhibitor with IC50 of 17 nM in a cell-free assay, about 5- and 110-fold selectivity over DYRK1A and DYRK2, respectively.
Chemical Information:
Molecular Weight (MW) 429.52 Formula
C24H27N7O
CAS No. 1594092-37-1 Solubility (25°C) * DMSO 85 mg/mL (197.89 mM) Water Insoluble Alcohol 1 mg/mL (2.32 mM)
Biological Activity:
Targets IC50
HIV protease 2.66 nM Ki
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.3282 mL 11.6409 mL 23.2818 mL 5 mM 0.4656 mL 2.3282 mL 4.6564 mL 10 mM 0.2328 mL 1.1641 mL 2.3282 mL 50 mM 0.0466 mL 0.2328 mL 0.4656 mL
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