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AZ191

AZ191

Catalog Number: CC7494 Rank: comment rank 5

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Description:

AZ191 is a potent and selective DYRK1B inhibitor with IC50 of 17 nM in a cell-free assay, about 5- and 110-fold selectivity over DYRK1A and DYRK2, respectively.

Chemical Information:

Molecular Weight (MW) 429.52
Formula

 

C24H27N7O

 

CAS No. 1594092-37-1
Solubility (25°C) * DMSO 85 mg/mL (197.89 mM)
Water Insoluble
Alcohol 1 mg/mL (2.32 mM)


Biological Activity:

Targets
IC50
HIV protease
2.66 nM Ki


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.3282 mL 11.6409 mL 23.2818 mL
5 mM 0.4656 mL 2.3282 mL 4.6564 mL
10 mM 0.2328 mL 1.1641 mL 2.3282 mL
50 mM 0.0466 mL 0.2328 mL 0.4656 mL


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