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ABC294640

ABC294640

Catalog Number: CC7330 Rank: comment rank 5

Size Price Qty
$ 277.00
$ 683.00
$ 81.00
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Description:

ABC294640 is an orally bioavailable and selective sphingosine kinase-2 (SphK2) inhibitor with IC50 of approximately 60 μM. Phase 1/2.

Chemical Information:

Molecular Weight (MW) 380.91
Formula

 

C23H25ClN2O

 

CAS No. 915385-81-8
Solubility (25°C) * DMSO 76 mg/mL warmed (199.52 mM)
Water Insoluble
Alcohol 28 mg/mL (73.5 mM)


Biological Activity:

Targets
IC50
TNF-α
13 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.6253 mL 13.1265 mL 26.2529 mL
5 mM 0.5251 mL 2.6253 mL 5.2506 mL
10 mM 0.2625 mL 1.3126 mL 2.6253 mL
50 mM 0.0525 mL 0.2625 mL 0.5251 mL


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