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SGC-CBP30

SGC-CBP30

Catalog Number: CC7412 Rank: comment rank 5

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Description:

SGC-CBP30 is a potent CREBBP/EP300 inhibitor with IC50 of 21 nM and 38 nM in cell-free assays, respectively. Exhibits 40-fold and 250-fold selectivity for CBP over the first BRD of BRD4 (BRD4(1)) and BRD4(2) respectively.

Chemical Information:

Molecular Weight (MW) 509.04
Formula

 

C28H33ClN4O3

 

CAS No. 1613695-14-9
Solubility (25°C) * DMSO 100 mg/mL (196.44 mM)
Water Insoluble
Alcohol 100 mg/mL (196.44 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.9645 mL 9.8224 mL 19.6448 mL
5 mM 0.3929 mL 1.9645 mL 3.9290 mL
10 mM 0.1964 mL 0.9822 mL 1.9645 mL
50 mM 0.0393 mL 0.1964 mL 0.3929 mL


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