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SGC 0946

SGC 0946

Catalog Number: CC7235 Rank: comment rank 5

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Description:

SGC 0946 is a highly potent and selective DOT1L methyltransferase inhibitor with IC50 of 0.3 nM in a cell-free assay, is inactive against a panel of 12 PMTs and DNMT1.

Chemical Information:

Molecular Weight (MW) 618.57
Formula

 

C28H40BrN7O4

 

CAS No. 1561178-17-3
Solubility (25°C) * DMSO 100 mg/mL (161.66 mM)
Water Insoluble
Alcohol 100 mg/mL (161.66 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.6166 mL 8.0832 mL 16.1663 mL
5 mM 0.3233 mL 1.6166 mL 3.2333 mL
10 mM 0.1617 mL 0.8083 mL 1.6166 mL
50 mM 0.0323 mL 0.1617 mL 0.3233 mL


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