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Senexin A

Senexin A

Catalog Number: CC8676 Rank: comment rank 5

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Description:

Senexin A is a potent and selective inhibitor of CDK8 and its nearest relative, CDK19 with Kd values of 0.83 μM and 0.31 μM for CDK8 and CDK19 ATP site binding, respectively.

Chemical Information:

Molecular Weight (MW) 274.32
Formula

 

C17H14N4

 

CAS No. 1366002-50-7
Solubility (25°C) * DMSO 54 mg/mL (196.85 mM)
Water Insoluble
Alcohol 54 mg/mL (196.85 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 3.6454 mL 18.2269 mL 36.4538 mL
5 mM 0.7291 mL 3.6454 mL 7.2908 mL
10 mM 0.3645 mL 1.8227 mL 3.6454 mL
50 mM 0.0729 mL 0.3645 mL 0.7291 mL


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